We use A&D, which is a petroleum based cream. We use it with every diaper change and she never gets a rash. It has no odor (I don’t like the smell of Desitin personally) and always puts a barrier between the babies skin and their diaper. I’ve heard just using Vaseline works just as good, though I’ve not tried it personally. I know some people have a consideration about using petroleum jelly on babies skin, but I have seen zero bad effects and only good effects–namely, she never gets rashes when we use it.